Structural Biology and Molecular Biophysics

Latest articles

1. 1. Structural Biology and Molecular Biophysics

   Some mechanistic underpinnings of molecular adaptations of SARS-COV-2 spike protein by integrating candidate adaptive polymorphisms with protein dynamics

   Nicholas James Ose, Paul Campitelli ... Sefika Banu Ozkan

   Insights from integrating evolutionary predictions and protein dynamics unveil how specific mutations in the SARS-CoV-2 spike protein epistatically interact in order to influence spike protein interaction with human cells, potentially altering the virus's infectivity and immune evasion capabilities.
2. 1. Biochemistry and Chemical Biology
   2. Structural Biology and Molecular Biophysics

   7,8-Dihydroxyflavone is a direct inhibitor of pyridoxal phosphatase

   Marian Brenner, Christoph Zink ... Antje Gohla
3. 1. Structural Biology and Molecular Biophysics

   Structural features of heteromeric channels composed of CALHM2 and CALHM4 paralogs

   Katarzyna Drożdżyk, Martina Peter, Raimund Dutzler
4. 1. Structural Biology and Molecular Biophysics

   The substrate-binding domains of the osmoregulatory ABC importer OpuA transiently interact

   Marco van den Noort, Panagiotis Drougkas ... Bert Poolman

   Transient and weak interactions between the substrate-binding proteins of the ATP-binding cassette transporter OpuA can influence the transport efficiency.
5. 1. Structural Biology and Molecular Biophysics

   TMEM16 and TMEM63/OSCA proteins share a conserved potential to permeate ions and phospholipids

   Augustus J. Lowry, Pengfei Liang ... Yang Zhang
6. 1. Structural Biology and Molecular Biophysics

   CTFFIND5 provides improved insight into quality, tilt and thickness of TEM samples

   Johannes Elferich, Lingli Kong ... Nikolaus Grigorieff
7. 1. Structural Biology and Molecular Biophysics

   Additional feedforward mechanism of Parkin activation via binding of phospho-UBL and RING0 in trans

   Dipti Lenka, Shakti Dahe ... Atul Kumar
8. 1. Biochemistry and Chemical Biology
   2. Structural Biology and Molecular Biophysics

   Deciphering the actin structure-dependent preferential cooperative binding of cofilin

   Kien Xuan Ngo, Huong T Vu ... Taro Q.P. Uyeda
9. 1. Structural Biology and Molecular Biophysics

   A novel bivalent interaction mode underlies a non-catalytic mechanism for Pin1-mediated protein kinase C regulation

   Xiao-Ru Chen, Karuna Dixit ... Tatyana I Igumenova

   Integrated biophysical, structural, and in-cell approaches demonstrate a non-canonical and non-isomerizable binding motif-dependent mode of protein kinase C regulation by the peptidyl-prolyl isomerase Pin1 in mammalian cells.
10. 1. Structural Biology and Molecular Biophysics

    Divergent Folding-Mediated Epistasis Among Unstable Membrane Protein Variants

    Laura M. Chamness, Charles P. Kuntz ... Jonathan P. Schlebach